LCMS-2020 LC/MS System

The ultra high-speed LC/MS Prominence UFLC+LCMS-2020 improves the speed and reliability of HPLC analysis, offering dramatic improvements in lab productivity.

3 points yielding ultra high-speed, ultra high-sensitivity MS measurements

By incorporating the following innovative features into the LCMS-2020, the sharp peaks of ultra high-speed LC won't be missed:
  • UFswitching (high-speed positive/negative ionization mode switching)

To detect both positive ions and negative ions, measurements are performed while switching alternately between positive and negative ionization modes. With the LCMS-2020, ultra high-speed polarity switching is achieved by adopting a high voltage power source loaded with groundbreaking technology (patent pending).

  • UFscanning (high-speed scan measurements)

In MS scanning, a range of mass to charge ratios are determined in successive 0.1 m/z steps. This is controlled by applying a rapidly changing voltage to the quadrupole (quadrupole rods). By adopting new technology (patent pending), high ion transmission is achieved without sacrificing sensitivity or resolution, even during high-speed scans up to 15,000 u/sec. Very narrow UFLC peaks can now be properly detected in scan mode acquisition.

  • UFsensitivity (superior sensitivity and repeatability thanks to newly developed ion optics)
Superior sensitivity, repeatability, and linearity are achieved, thanks to the newly developed Qarray® optics.

The UFLC/MS, which continues the tradition of high-level data reliability from the well-received ultra high-speed LC Prominence UFLC, has now been released.

Dual Ion Source

The DUIS-2020 is an optional dual ion source for the LCMS-2020. The dual ion source continuously performs two types of ionization, ESI and APCI, which allows simultaneous analysis of samples suited to either ionization technique.
This increases laboratory efficiency by making it possible to analyze a wide range of chemical species. DUIS ionization is particularly useful in the confirmation of synthetic compounds, or for confirming reaction byproducts and other unknown substances. Pharmaceutical drug discovery groups or any laboratory analyzing both polar and non-polar analytes will benefit from the Dual Ion Source.

The Dual ion source simultaneously ionizes samples using two ionization methods - electrospray ionization (ESI), which is suitable for high polarity compounds, and atmospheric pressure chemical ionization (APCI), which is suitable for low-to-medium polarity compounds. Therefore, it is capable of ionizing a wide range of compounds, including chemical classes from low to high polarity.

 

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